McGee MC, Zhang T, Magazine N, Islam R, Carossino M and Huang W†. PD-1 and ICOS counterregulate tissue resident regulatory T cell development and IL-10 production during flu. Front Immunol. (2022) 13:984476.
Chen W#, Huang W#, Xue Y, Chen Y, Qian W, Ma J, August A, Wnag J, Zheng SG, Lin J. Neuropilin-1 identifies a new subpopulation of TGF-β-induced Foxp3+ regulatory T cells with potent suppressive function and enhanced stability during inflammation. Front Immunol. (2022) 13:900139.
McGee MC and Huang W†. Evolutionary conservation and positive selection of Influenza A Nucleoprotein CTL epitopes for universal vaccination. J Med Virol. (2022), 94(6):2578-2587.Editor’s Choice
Magazine N, Zhang T, Wu Y, McGee MC, Veggiani G, and Huang W†. Mutations and Evolution of the SARS-CoV-2 Spike Protein. Viruses. (2022) 14(3), 640.
Elmore J, Carter C … …, Huang W, Singh A, and August A. Itk independent development of Th17 responses during Hypersensitivity pneumonitis driven lung inflammation. Commun Biol. (2022) 5, 162.
Tang J, Liu J, Yan Q, Gu Z, August A, Huang W†, and Jiang Z†. Konjac glucomannan oligosaccharides attenuate intestinal inflammation through SIGNR1-mediated regulation of alternatively activated macrophages. Mol Nutr Food Res. (2021) 65(20):e2001010.
Chen J, Zhang X, Li L, Ma X, Yang C, Liu Z, Li C, Fernandez-Cabezudo MJ, al-Ramadi BK, Wu C, Huang W, Zhang Y, Zhang Y, and Liu W. Farnesyl pyrophosphate is a new danger signal for acute cell death through TRPM2. PLoS Biol. (2021) 19 (4), e3001134.
Mammadli M, Huang W, Sultana A, Cheng Y, Tong W, Pu J, Gentile T, August A, and Karimi M. Targeting Interleukin-2-Inducible T-cell Kinase (ITK) differentiates GVL and GVHD in allo-HSCT. Front Immunol. (2021) 11, 3082.
Ding H, Yin S, Cheng Y, Cai Y, Huang W†, and Deng W†. Neurologic manifestations of non-hospitalized patients with COVID-19 in Wuhan, China. MedComm. (2020) 1 (2), 253-256.
Ding H, Deng W, Ding L, Ye X, Yin S, and Huang W†. Glycyrrhetinic acid and its derivatives as potential alternative medicine to relieve symptoms in non-hospitalized COVID-19 patients. J Med Virol. (2020) 92 (10), 2200-2204.
Owen DL, Mahmud SA, Sjaastad LE, Williams JB, Simeonov DR, Ruscher R, Huang W, ……, and Farrar MA. Thymic regulatory T cells arise via two distinct developmental programs. Nat Immunol. (2019) 20(2): 195-205.
Huang W†, Solouki S, Carter C, Zheng SG, and August A†. Beyond type 1 regulatory T cells: co-expression of LAG3 and CD49b in IL-10-producing T cell lineages. Front Immunol. (2018) 9:2625.
Battu S, Afroz S, Giddaluru J, Naz S, Huang W, Khumukcham SS, et al. Amino acid starvation sensing dampens IL-1β production by activating riboclustering and autophagy. PLoS Biol. (2018) 16(4): e2005317.
Selected Publications prior to 2018:
Huang W†, Solouki S, Koylass N, Zheng SG, and August A†. ITK signalling via the Ras/IRF4 pathway regulates the development and function of Tr1 cells. Nat Commun. (2017) 8, 15871.
Huang W, Jeong AR, Kannan AK, Huang L, and August A. IL-2-inducible T cell kinase tunes T regulatory cell development and is required for suppressive function. J Immunol. (2014) 193(5):2267-72.
Huang W, Qi Q, Hu J, Huang F, Laufer TM, and August A. Dendritic cell-MHC class II and Itk regulate functional development of regulatory innate memory CD4+ T cells in bone marrow transplantation. J Immunol. (2014) 192(7):3435-41.
Huang W, Huang F, Kannan AK, Hu J, and August A. ITK tunes IL-4 induced development of innate memory CD8+ T cells in a γδ and invariant NKT cell-independent manner. J Leukoc Biol. (2014) 96(1):55-63.
Huang W, Hu J, and August A. Cutting Edge: Innate memory CD8+ T cells are distinct from homeostatic expanded CD8+ T cells and rapidly respond to primary antigenic stimuli. J Immunol. (2013) 190(6):2490-4.